水産食品衛生学研究室
研究業績
2014
辰野 竜平・反町 太樹・谷山 茂人・大城 直雅・久保 弘文・高谷 智裕・荒川 修：腐肉食性小型巻貝2種に対するフグ毒給餌実験. 食品衛生学雑誌, 55, 152-156 (2014).
Shanshan Jiang, K. Kuwano, N. Ishikawa, M. Yano, T. Takatani, O. Arakawa：Production of domoic acid by laboratory culture of the red alga Chondria armataOriginal Research Article. Toxicon, Volume 92, 1-5 (2014).
Hsiao-Chin Jen, Thi Anh-Tuyet Nguyen, Ya-Jung Wu, T. Hoang, O. Arakawa, Wen-Feng Lin, Deng-Fwu Hwang: Tetrodotoxin and paralytic shellfish poisons in gastropod species from Vietnam analyzed by high-performance liquid chromatography and liquid chromatography–tandem mass spectrometryOriginal Research Article. Journal of Food and Drug Analysis, Volume 22, Issue 2, 178-188 (2014).
S. Itoi, S. Yoshikawa, K. Asahina, M. Suzuki, K. Ishizuka, N. Takimoto, R. Mitsuoka, N. Yokoyama, A. Detake, C. Takayanagi, M. Eguchi, R. Tatsuno, M. Kawane, S. Kokubo, S. Takanashi, A. Miura, K. Suitoh, T. Takatani, O. Arakawa, Y. Sakakura, H. Sugita, et al : Larval pufferfish protected by maternal tetrodotoxinOriginal Research Article, Toxicon, Volume 78, 35-40 (2014).
2013
Okita, Kogen・Yamazaki, Hideki・Sakiyama, Kazutaka・Yamane, Hikaru・Niina, Shinya・Takatani, Tomohiro・ Arakawa, Osamu・Sakakura, Yoshitaka：Puffer smells tetrodotoxin. Ichthyological Research, 60(4), 386-389 (2013).
谷口香織・髙尾秀樹・新名真也・山中祐二・岡田幸長・中島梨花・王 俊杰・辰野竜平・阪倉良孝・高谷智裕・荒川 修・野口玉雄: 天然トラフグ肝臓の毒性分布. 食品衛生学雑誌, 54, 277-281 (2013).
K. Okita, T. Takatani, J. Nakayasu, H. Yamazaki, K. Sakiyama, K. Ikeda, O. Arakawa and Y. Sakakura: Comparison of the localization of tetrodotoxin between wild pufferfish Takifugu rubripes juveniles and hatchery-reared juveniles with tetrodotoxin administraton. Toxicon, 71, 128-133 (2013).
R. Tatsuno, M. Shikina, Y. Shirai, J. Wang, K. Soyano, G.N. Nishihara, T. Takatani, and O. Arakawa: Change in the transfer profile of orally administered tetrodotoxin non-toxic cultured pufferfish Takifugu rubripes depending of its development stage. Toxicon, 65, 76-80 (2013).
R. Tatsuno, M. Shikina, K. Soyano, K. Ikeda, T. Takatani, and O. Arakawa: Maturation-associated changes in the internal distribution of tetrodotoxin in the female goby Yongeichthys criniger. Toxicon, 63, 64-69 (2013).
R. Tatsuno, K. Yamaguchi, T. Takatani, and O. Arakawa: RT-PCR- and MALDI-TOF mass spectrometry-based identification and discrimination of isoforms homologous to pufferfish saxitoxin- and tetrodotoxin-binding protein in the plasma of non-toxic cultured pufferfish (Takifugu rubripes). Bioscience, Biotechnology, and Biochemistry, 77, 208-212 (2013).
S. Itoi, S. Yoshikawa, R. Tatsuno, M. Suzuki, K. Asahina, S. Yamamoto, S. Takanashi, T. Takatani, O. Arakawa, Y. Sakakura, and H. Sugita: RT-PCR- and MALDI-TOF mass spectrometry-based identification and discrimination of isoforms homologous to pufferfish saxitoxin- and tetrodotoxin-binding protein in the plasma of non-toxic cultured pufferfish (Takifugu rubripes). Bioscience, Biotechnology, and Biochemistry, 77, 208-212 (2013).
2012
D. Mebs, M. Yotsu-Yamashita, H.M. Seitz, O. Arakawa: Tetrodotoxin does not protect red-spotted newts, Notophthalmus viridescens,from intestinal parasites. Toxicon, 60, 66-69 (2012).
J. Wang, T. Araki, R. Tatsuno, S. NIna, K. Ikeda, T. Takatani, and O. Arakawa: Transfer profile of orally and intramuscularly administered tetrodotoxin to artificial hybrid specimens of pufferfish Takifugu rubripes and Takifugu porphyreus. Food Hyg. Soc. Jpn., 45, 73-75 (2012).
D. Mebs, O. Arakawa and M. Yotsu-Yamashita: Tissue distribution of tetrodotoxin in the red-spotted newt Notophthalmus viridescens.Toxicon, 55, 1353-1357 (2012).
2011
S. Miki, K. Ikeda, Y. Oba, H. Satone, M. Honda, Y. Shimasaki, N. Onikura, O. Arakawa and Y. Oshima: Tributyltin in blood of marine fish collected from a coastal area of northern Kyushu, Japan. Marine Pollution Bulletin, 62, 2533-2536 (2011).
J. Wang, T. Araki, R. Tatsuno, S. NIna, K. Ikeda, M. Hamasaki, Y. Sakakura, T. Takatani, and O. Arakawa: Transfer profile of intramuscularly administered tetrodotoxin to artificial hybrid specimens of pufferfish, Takifugu rubripes and Takifugu niphobles. Toxicon, 58, 565-569 (2011).
2010
K. Ikeda, Y. Emoto, R. Tatsuno, J. Wang, L. Ngy, S. Taniyama, T. Takatani, and O. Arakawa: Maturaton-associated changes in toxicity of the pufferfish Takifugu poecilonotus. Toxicon, 55, 289-297 (2010).
2009
K. Ikeda, Y. Murakami, Y. Emoto, L. Ngy, S. Taniyama, M. Yagi, T. Takatani, and O. Arakawa: Transfer profile of intramuscularly administered tetrodotoxin to non-toxic cultured specimens of the pufferfish Takifugu rubripes. Toxicon, 53, 99-103 (2009).
2008
L. Ngy, K. Tada, C.-F. Yu, T. Takatani, and O. Arakawa: Occurrence of paralytic shellfish toxins in Cambodian MekongpufferfishTetraodon turgidus: selective toxin accumulation in the skin. Toxicon, 51, 280-288 (2008).
2007
L. Ngy, C.-F. Yu, T. Takatani, and O. Arakawa: Toxicity assessment for horseshoe crab Carcinoscorpius rotundicauda collected from Cambodia. Toxicon, 49, 843-847 (2007).
M. Samsur, T. Takatani, Y. Yamaguchi, T. Sagara, T. Noguchi, and O. Arakawa: Accumulation and elimination profiles of paralytic shellfish poison in the short-necked clam Tapes japonica fed with the toxic dinoflagellateGymnodinium catenatum. J. Food Hyg. Soc. Japan, 48, 13-18 (2007).
2006
M. Samsur, Y. Ymaguchi, T. Sagara, T. Takatani, O. Arakawa, and T. Noguchi: Accumulation and depuration profiles of PSP toxins in the short-necked clam Tapes japonica fed with the toxic dinoflagellateAlexandrium catenella. Toxicon, 48, 323-330 (2006).
K. Ikeda, B.A.V. Maran, S. Honda, S. Ohtsuka, O. Arakawa, T. Takatani, M. Asakawa, and G. A. Boxshall: Accumulation of tetrodotoxin(TTX) in Pseudocaligus fugu, a parasitic copepod from panther puffer Takifugu pardalis, but without vertical transmission - using animmunoenzymatic technique. Toxicon, 48, 116-122 (2006).
T. Noguchi, O. Aarakawa, and T. Takatani: TTX accumulation in pufferfish. CBP Part D, 1, 145-152 (2006).
T. Noguchi, O. Aarakawa, and T. Takatani: Toxicity of the pufferfish Takifugu rubripes cultured in netcages at sea or aquaria on land.CBP Part D, 1, 153-157 (2006).
2005
高谷智裕・荒川 修・野口玉雄：中国で頻発している小型巻貝による食中毒について．食衛誌, 46, 208-209 (2005).
本田俊一・荒川 修・高谷智裕・橘 勝康・八木基明・谷川昭夫・野口玉雄：テトロドトキシン添加飼料投与による養殖トラフグTakifugu rubripesの毒化．日水誌, 71, 815-820 (2005).
本田俊一・一部哲哉・荒川 修・高谷智裕・橘 勝康・八木基明・谷川昭夫・野口玉雄：フグ毒添加飼料を投与した養殖トラフグのヒツジ赤血球に対する抗体産生能と脾臓細胞の幼若化反応．水産増殖, 53, 205-210 (2005).
2004
M. B. Tanu, Y. Mahmud, O. Arakawa, T. Takatani, H. Kajihara, K. Kawatsu, Y. Hamano, M. Asakawa, K. Miyazawa, and T. Noguchi: Immunoenzymatic visualization of tetrodotoxin (TTX) in Cephalothrix species (Nemertea: Anopla: Palaeonemertea: Cephalotrichidae) andPlanocera reticulata (Platyhelminthes: Turbellaria: Polycladida: Planoceridae). Toxicon , 44, 515-520 (2004).
野口玉雄・高谷智裕・荒川 修：囲い養殖法により養殖されたトラフグの毒性. 食衛誌, 45, 146-149 (2004).
K. Nakashima, O. Arakawa, S. Taniyama, M. Nonaka, T. Takatani, K. Yamamori, Y. Fuchi, and T. Noguchi: Occurrence of saxitoxins as a major toxin in the ovary of marine puffer Arothron firmamentum. Toxicon, 43, 207-212 (2004).
2003
S. Taniyama, O. Arakawa, M. Terada, S. Nishio, T. Takatani, Y. Mahmud, and T. Noguchi: Ostreopsis sp., a possible origin of palytoxin (PTX) in parrotfish Scarus ovifrons. Toxicon, 42, 29-33 (2003).
Y. Mahmud, O. Arakawa, A. Ichinose, M. B. Tanu, T. Takatani, K. Tsuruda, K. Kawatsu, Y. Hamano, and T. Noguchi: Intracellular visualization of tetrodotoxin (TTX) in the skin of a puffer Tetraodon nigroviridis by immunoenzymatic technique. Toxicon, 41, 605-611 (2003).
Y. Mahmud, K. Okada, T. Takatani, K. Kawatsu, Y. Hamano, O. Arakawa, and T. Noguchi: Intra-tissue distribution of tetrodotoxin in two marine puffers Takifugu vermicularis and Chelonodon patoca. Toxicon, 41, 13-18 (2003).
2002
S. Taniyama, Y. Mahmud, M. Terada, T. Takatani, O. Arakawa, and T. Noguchi: Occurrence of a food poisoning incident by palytoxin from aserranidEpinephelus sp. in Japan. J. Natural Toxins, 11, 277-282 (2002).
K. Tsuruda, O. Arakawa, K. Kawatsu, Y. Hamano, T. Takatani, and T. Noguchi: Secretory glands of tetrodotoxin in the skin of a Japanese newt Cynops pyrrhogaster. Toxicon, 40, 131-136 (2002).
M.B. Tanu, Y. Mahmud, T. Takatani, K. Kawatsu, Y. Hamano, O. Arakawa, and T. Noguchi: Localization of tetrodotoxin in the skin of abrackishwater puffer Tetraodon steindachneri on the basis of immunohistological study. Toxicon, 40, 103-106 (2002).
2001
M.B. Tanu, Y. Mahmud, K. Tsuruda, O. Arakawa, and T. Noguchi: Occurrence of tetrodotoxin in the skin of a rhacophoridid frogPolypedates sp. from Bangladesh. Toxicon, 39, 937-941 (2001).
K. Tsuruda, O. Arakawa, and T. Noguchi: Toxicity and toxin profiles of the newt, Cynops pyrrhogaster from Western Japan. J. Natural Toxins, 10, 79-89 (2001).
S. Taniyama, Y. Mahmud, M.B. Tanu, T. Takatani, O. Arakawa, and T. Noguchi: Delayed haemolytic activity by the freshwater
puffer Tetraodon sp. toxin. Toxicon, 39, 725-727 (2001).
S. Taniyama, Y. Mahmud, M. B. Tanu, T. Takatani, O. Arakawa, T. Noguchi. Delayed haemolytic activity by the freshwater pufferTetraodon sp. toxin. Toxicon, 39 (5), 725-727 (2001).
1998
L. Zaman, O. Arakawa, A. Shimosu, Y. Shida and Y. Onoue: Occurrence of a methyl derivative of saxitoxin in Bangladeshi freshwater puffers. Toxicon. 36, 627-630 (1998).
T. Takatani, H. Akaeda, T. Kaku, M. Miyamoto, H. Mukai and T. Noguchi. Paralytic shellfish poison infestation to oyster Crassostrea gigasdue to dinoflagellate Gymnodinium catenatum in Amakusa Islands, Kumamoto Prefecture. Journal of the Food Hygiene Society of Japan. 39(4), 292-295 (1998).
T. Takatani, T. Morita, A. Anami, H. Akaeda, Y. Kamijyo, K. Tsutsumi and T. Noguchi. Appearance of Gymnodinium catenatum in association with the toxification of bivalves in Kamae, Oita Prefecture, Japan. Journal of the Food Hygiene Society of Japan. 39(4), 275-280 (1998).
H. Akaeda, T. Takatani, A. Anami and T. Noguchi. Mass outbreaks of a food poisoning due to ingestion of an oyster at Tamano-ura, in Goto Islands, Nagasaki, Japan. Journal of the Food Hygiene Society of Japan. 39(4), 272-274 (1998).
1997
A. Kungsuwan, O. Arakawa, M. Promdet and Y. Onoue: Occurrence of paralytic shellfish poisons in thai freshwater puffers. Toxicon. 35, 1341-3146 (1997).
L. Zaman, O. Arakawa, A. Shimosu, and Y. Onoue: Occurrence of paralytic shellfish poison in Bangladeshi freshwater puffers. Toxicon. 35, 423-431 (1997).
L. Zaman, O. Arakawa, A. Shimosu, Y. Onoue, S. Nishio, Y. Shida and T. Noguchi: Two new isomers of domoic acid from a red alga,Chondria armata. Toxicon. 35, 205-212 (1997).
T. Takatani, H. Akaeda, O. Arakawa and T. Noguchi. Occurrence of paralytic shellfish poison (PSP) in the bivalves, along with the mossworm adherent to their shells, collected from Fukue Island, Nagasaki, Japan during 1995 to 1996. Journal of the Food Hygiene Society of Japan, 38(6), 430-434 (1997).
K. Tsuruda, T. Takatani, T. Noguchi, H. Akaeda and T. Matsuo. Toxicity of Japanese newt, Cynops pyrrhogaster at Nagasaki Prefecture. Transactions of the Nagasaki Biological Society, No.48, 158-161. (1997).
A. Anami, K. Tsuruda, T. Takatani, T. Morita, H. Akaeda, T. Noguchi, H. Suzuki and T. Matsuo. Toxicity of Atergatis floridus crabs collected at Nagasaki Prefecture. Transactions of the Nagasaki Biological Society, No.48, 155-157. (1997).
1995
O. Arakawa, S. Nishio, T. Noguchi, Y. Shida and Y. Onoue: A new saxitoxin analogue from a xanthid crab Atergatis floridus. Toxicon. 33, 1577-1584. (1995).
Md. S. Ahmed, S. Khan, O. Arakawa and Y. Onoue: Properties of hemagglutinins newly separated from toxic phytoplankton. Biochimica et Biophysica Acta-General Subjects. 1243, 509-512. (1995).
1994
O. Arakawa T. Noguchi, Y. Shida and Y. Onoue: Occurrence of carbamoyl-N-hydroxy derivatives of saxitoxin and neosaxitoin in a xanthid crab Zosimus aeneus. Toxicon. 32, 175-183. (1994).